The overarching goal of The Virtual Brain Cloud (TVB-Cloud) is personalized prevention and treatment of dementia. To achieve generalizable results that help individual patients, The Virtual Brain Cloud integrates the data of large cohorts of patients and healthy controls through multi-scale brain simulation using The Virtual Brain (or TVB) simulator. There is a need for infrastructures for sharing and processing health data at a large scale that comply with the EU general data protection regulations (or GDPR). The VirtualBrainCloud consortium closes this gap, making health data actionable. Elaborated data protection concepts minimize the risks for data subjects and allow scientists to use sensitive data for research and clinical translation.