The central goal of this project is the development of a cloud-based platform for biomedical research and clinical decision-making that helps to improve early patient-specific diagnosis and treatment of NDD and has substantial potential for significant positive socioeconomic impact.
The platform integrates several aims that revolve around early diagnosis, prognosis, and personalized treatment of neurodegenerative diseases (NDD) like Alzheimer’s disease (AD) and Parkinson’s disease (PD). It is becoming increasingly clear that meeting this objective requires a multifactorial approach that takes into account individual genetic, metabolic and environmental aspects, and that integrates them with the understanding of the biophysical processes underlying NDD.
TheVirtualBrain: Interactive Brainweb Atlas
TheVirtualBrain Atlas, a collaborative project with Human Brain Project (HBP), has been getting a lot of attention lately: Have you heard about the new interactive Brainweb Atlas? You can flip, rotate, and click around this online 3D model to learn about the different regions of the brain and their functions.
Try out - https://t.co/R3fzz1R0sH
Brain Connectivity Workshop - June 2020
We are excited to announce that Dr. Petra Ritter will talk at the Brain Connectivity Workshop in Toronto in June 2020. Registration for the event will open in January 2020 and until then you can sign up for more info or check out the preliminary program here.
The aim of Brain Connectivity Workshop is to establish a dialogue between researchers in computational neuroscience, neuroscience methodology and experimental neuroscience about the emerging field of brain connectivity.
Next year's Brain Connectivity Workshop is conveniently before OHBM in Montreal, Canada (June 26-30).
Advances in Alzheimer's and Parkinson's Therapies Fokus Meeting
2- 5 April 2020 in Vienna
We invite you to join us for the 2nd AAT-AD/PD Focus Meeting 2020 in Vienna, Austria. The first AAT-AD/PD Focus Meeting 2018 was held in Torino, Italy with 1337 participants.
The Meeting will present all the latest breakthroughs in treatment, translational R&D, early diagnosis, drug development and clinical trials in Alzheimer’s, Parkinson’s and other related neurological disorders.
More here: https://aat-adpd.kenes.com/
Topic in Frontiers Neuroinformatics: ‘Brain Modeling of Neurodegenerative Disorders’
Contributions until February 29 2020
We'd like to bring attention to a new Research Topic in Frontiers Neuroinformatics: ‘Brain Modeling of Neurodegenerative Disorders’. We invite for your contributions!
Please contribute to the article collection:
TVB-cloud at Mobile World Congress Barcelona 2020
Barcelona, Spain 24-27 February, 2020
We are excited to announce that the The Virtual Brain and Virtual Brain Cloud will have a booth at the Mobile World Congress in Barcelona in February 24-27 2020. We will be showing our work alongside the Human Brain Project and industry partners Eodyne and Indoc.
Medical University Charité's 26th Neurokolloquium
February 15 2020, Berlin, Germany
The 26th Neurokolloquium will be held on the 15th of February at the Charité Campus Virchow Klinikum. Neurokolloquium is an annual symposium put on by the Charité Clinic and University Outpatient Department for Neurology, during which a variety of lectures and presentations are held on topics from the entire spectrum of work done in the Neurology Department. Themes include therapy, diagnosis, historical content and controversial topics from the field. As part of the day's events, Dr. Petra Ritter will present a guest lecture on The Virtual Brain, covering how brain simulations can aid in better understanding and treatment of neurological illnesses.
Lectures and presentations will be held in German. The event is free for employees and students of the Charité Neurology Department. The fee for external participants is 20€. Please find further details on the program and how to register here.
The Virtual Brain at the Human Brain Project Summit
Athens, February 3 - 6 2020
Meet the TVB team at the Human Brain Project Summit & Open Day in Athens from February 3 to 6!
We will present at the "Explore the Brain" EBRAINS booth on Open day, February 3rd and have a dedicated TVB session on February 5th. Find out about all the TVB tools and services that we made available via EBRAINS!
Dr. Petra Ritter & Paul Triebkorn present The Virtual Brain at Urania
Urania Berlin, January 21 2020
Petra Ritter and Paul Triebkorn will present The Virtual Brain at Urania Berlin on January 21st, 2020. Urania Berlin is one of the leading centers of dialog between science, the humanities and the public. We are excited to join the many leading scientists who deliver lectures and talks in their areas of research at Urania. The talk will be a part of a series called Berlin Brains 2020, during which neuroscientists working in Berlin will present their current work to the public.
Find out more details about the event here.
Dr. Petra Ritter to give a lecture on TVB at Bernstein Center Berlin
January 20, 2020, Berlin, Germany
Dr. Petra Ritter will be holding a lecture on The Virtual Brain at the Bernstein Center for Computational Neuroscience Berlin on January 20th, 2019. The lecture will begin at 4pm in the BCCN lecture hall. Guests are welcome! Please send an email to Dr. Ritter for registration.
TVB-Cloud is partnering project of HBP
July 16 2019
Virtual Brain Cloud became Partnering Project of the EU Flagship Human Brain Project.
Videos on TheVirtualBrain / Cloud
Conferences are an important channel for the exchange of information between researchers. The VirtualBrainCloud consortium will announce conference contributions here.
Scientific journals are the main forum for the VirtualBrainCloud (TVB-cloud) consortium to present the latest project results. The TVB-cloud partners will guarantee open access for all VirtualBrainCloud publications.
The VirtualBrainCloud consortium will publish several reports on various project related topics. Please find here a collection of public documents by the TVB-cloud partners.
Please find here a collection of articles and publications by the VirtualBrainCloud members and articles on the project in the news.
VirtualBrainCloud advisory board
Magali Haas, MD, Ph.D.
CEO & President Cohen Veterans Bioscience
Peter-Andreas Löschmann, Ph.D.
Senior Director Corporate Affairs & Senior Medical Director - Pfizer Pharma GmbH Germany
Stefano Cappa, Ph.D.
Professor of Cognitive Neuroscience at the University Vita-Salute S. Raffaele of Milan
Fabrizio Tagliavini, MD
Scientific Director IRCCS Foundation, "Carlo Besta" Neurological Institute, Milan, Italy
Charité Universitätsmedizin Berlin, Germany
The CHARITE is Europe´s largest University Hospital that combines leadership experience a strong track record for development of innovative technologies and combining science with outreach projects to engage public.
Petra Ritter’s BrainModes group is one of the leaders in the field of multimodal brain imaging with simultaneous EEG-fMRI with research focus on state-dependent brain processing and computational modelling of large-scale brain signals. Strong expertise exists in the fields of clinical neurosciences, merging multimodal imaging and computational modelling to elucidate complex principles of brain function, data processing, analysis and visualization.
Aix-Marseilles University Aix en Provence & Marseilles, France
The Institut de Neurosciences des Systèmes is a multidisciplinary research institute located in Marseille. The core faculty is composed of members of academic and clinical institutions. The research has been developed around a common concept, the dynamic brain, integrating experimental, theoretical and clinical approaches towards the understanding of brain function and dysfunction.
The Theoretical Neuroscience group led by Viktor Jirsa aims to uncover the mechanisms underlying the spatiotemporal organization of large-scale brain networks in physiology including aging and disease with a particular interest in epilepsy and neurodegenerative diseases.
Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany
The Department of Bioinformatics Fraunhofer SCAI is a leading institute in applied research and development in the field of information extraction
/ semantic text analysis, integrative data semantics, and modeling of neurodegenerative diseases and neuropsychiatric conditions. The Department of Bioinformatics is working closely with industrial partners to enhance their competitiveness through mediating knowledge and technology transfer from academic research to industrial applications. Positioned at the boundary between commercial and academic research, Fraunhofer SCAI maintains strong links with both communities.
University of Oxford, United Kingdom
The University of Oxford is an internationally recognised centre of excellence for biomedical and clinical research and teaching.
The largest group of the Translational Neuroscience and Dementia Research laboratory is the Translational Informatics team, led by Dr Alejo Nevado-Holgado. The laboratory has research experience developing AD biomarkers and has led the field on using blood as the substrate tissue for such biomarkers. Such blood-based biomarkers are the only practical solution towards screening wide sections of the general population, and early detecting those who are developing AD years earlier than currently possible.
Institut de Cerveau et de la Moelle Epinière, Paris, France
The Institut du Cerveau et de la Moelle épiniere (ICM) is an international brain and spinal cord research center whose innovative concept and structure make it the only institute of its kind in the world. The institute brings patients, doctors and researchers together with the aim to rapidly develop treatments for disorders of the nervous system and enable patients to benefit from them as quickly as possible. Its teams carry out cutting-edge research on cellular and experimental models, neuroimaging & behavioral neuroscience, as well as data analysis. Being involved in several cohorts of patients allows the ICM to perform proeficient translational research.
The ARAMIS Lab is one of the leading teams in Europe for the modelling of neurodegenerative diseases. It has proposed original approaches for building brain models by the integration of multimodal data sets combining information from clinical, imaging and genomic data. The team has a strong expertise in imaging science, network theory, statistical and machine learning, and mathematical modelling. It has developed new computational approaches for modelling brain structure and function and has applied them in a large array of clinical studies, and in particular in the field of neurodegenerative diseases (Alzheimer’s Disease, Parkinson’s Disease, Multiple Sclerosis).
Forschungszentrum Jülich, Germany
The Forschungszentrum Jülich (FZJ), is a member of the Helmholtz Association of German Research Centres and is one of the largest interdisciplinary research centers in Europe. FZJ has an outstanding track-record in multi-modal high-throughput neuroimaging analysis, the investigation of brain structure-function relationships in health and disease as well as the development and application of big data approaches towards the understanding of brain organization.
The Institute of Neuroscience and Medicine (INM-7) lead by Simon Eickhoff works towards a more detailed characterization of the organization of the human brain and its interindividual variability in order to better understand its changes in advanced age as well as neurological and psychiatric disorders. Machine learning algorithms are developed and applied for predictive modeling of interindividual variability and pathology.
The Jülich Supercomputing Centre (JSC) operates supercomputers which are among the largest in Europe. The JSC undertakes research and development in HPC architectures, performance analysis, HPC applications, data analytics, federated infrastructures, and networking. The JSC's SimLab Neuroscience supports neuroscientists in using supercomputing and data resources for their research, and is engaged in collaborative research and development of HPC-based methods and tools for neuroscience.
Institut National de Recherche en Informatique et Automatique, Paris, France
Inria is the only French public research body fully dedicated to computational sciences. Inria’s mission is to pursue excellent research in computer science and applied mathematics in order to play a major role in resolving scientific, societal and industrial challenges.
Bertrand Thirions group has a recognised expertise both in machine learning and functional brain imaging data analysis. The Parietal team is a leading group in the design of dedicated machine learning techniques for data-driven regions segmentation of rest fMRI, and the creations of the tangent approach for functional connectivity analysis, that outperforms all other connectivity estimators on the challenging task of connectome estimation.
Fundació Institut de Bioenginyeria de Catalunya, Barcelona, Spain
IBEC is one of the Spanish research centres of excellence at the highest international level in terms of research, training, human resources, outreach and technology transfer.
The “Synthetic Perceptive, Emotive and Cognitive Systems (SPECS)” group led by Prof. Paul Verschure is a multidisciplinary research group focusing its research activities to study and synthesize the neuronal, psychological and behavioural principles underlying perception, emotion and cognition. SPECS perform interdisciplinary research in the domains of technology, cognitive science and humanities, and have a long-standing tradition in the domains of computational neuroscience, cognitive science and interactive systems.
University of Helsinki, Finland
The Neuroscience Center (NC) is an independent research and teaching institute at the University of Helsinki.
The Palva-Lab has made pioneering contributions in the fields of electrophysiological human brain connectomics and characterization of complex spatio-temporal brain dynamics. The Palva team has an extensive track record for using source-reconstructed MEG/EEG analyses of connectivity and dynamics to uncover the mechanistic roles in cognitive functions. The group has studied the roles of dysconnectivity and dysdynamics in brain disorders such as schizophrenia, epilepsy, depression, and anxiety.
University of Genoa, Italy
The University of Genoa (UNIGE) is one of the most ancient of the European large universities.
The Gabriele Arnulfo team are experts in signal processing mainly involving neuronal time series. Unit members have extensive expertise in Biomedical engineering topics including advanced signal processing of electrophysiology as well as imaging modalities. Several members have active involvement in the construction of informatic applications based on web for the support of multicentric with particular attention to studies dealing with the application of standardized systems in medicine and biology.
Universidad Complutense de Madrid, Spain
The Universidad Complutense de Madrid (UCM) is one of the largest Universities in Spain with high-level technological scientific infrastructure.
The Laboratory of Cognitive and Computational Neuroscience (LCCN) is part of the Center for Biomedical Technology (CTB), a multi-university research centre with deep experience on functional neuroimaging techniques, behavioural methods and data analysis, carry out research on cognitive and computational neuroscience, neuroimaging, nanomedicine, computational system biology, connexiopathies, biomagnetism, biomechanics, biomedical informatics, and tele-rehabilitation technologies. In particular, LCCN is pointed to the study of different stages of dementia as well as to reconfiguration phenomena associated with brain damage.
Codebox Computerdienste GmbH, Stuttgart, Germany
Codebox has a wide range of expertise in the development of software and has been in charge of the technical architecture, data-infrastructure and visualization technology of The Virtual Brain project including its conception, development and implementation. The modus operandi of Codebox is “distributed software development” to leverage optimal expertise for a particular project. Codebox has a good reputation for delivering robust software-architecture in scientific programming.
Codebox and CodeMart have a collaborative history of software development that has led to the successful professional design and release of The Virtual Brain (TVB) platform for large-scale mean-field simulations based on connectomic data and analysis of empirical and simulated activity.
Codemart SRL, Cluj Napoca, Romania
Codemart is certified under ISO 9001, for the procedure of delivering client tailored software solutions. Codemart is intimately familiar with architecting, building and maintaining fairly large codebases for various industries in many countries. Ranging from neuroscience projects, to printers coordination solutions, Codemart maintained recurrent collaborations with its final clients over the years. Codemart is a closely knit team of specialists, having long experience in computer science and training at the Technical University of Cluj Napoca. Codemart have made it part of the procedure to write automated test, have continuous integration builds and try various optimization techniques for each of the solutions tailored.
Eodyne Systems SL, Barcelona, Spain
Eodyne is specialised in the development and commercialization of advanced science-based neurorehabilitation software with an emphasis on functional recovery post stroke which will provide a driver for integration across the broad set of activities. Eodyne advances a network science-based paradigm for neurorehabilitation by taking a multiscale network-based perspective from genetics and connectomics to behaviour.
Eodyne’s expertise is on the development of algorithms and applications with virtual and augmented reality, immersive systems and infrastructures, scientific visualization, modeling and simulation, big data approaches on clinical data.
University of Vienna, Austria
The Department of Innovation and Digitalisation in Law, being part of University's of Vienna School of Law, was founded in October 2017 to face new legal questions and challenges in the 21st century. The department deals with legal questions surrounding IT/IP law from a European perspective, with an emphasis on data protection and data security law. The head of the department is Prof. Dr. Nikolaus Forgó, a full professor of Intellectual Property and technology law, whose objectives, among others, are to stratify, bundle and foster the existing research initiatives on digitalisation and IT at the law school. One important focus is the participation in third-party funded legal research, especially EU-founded projects.
The Department of Innovation and Digitalisation in Law will serve as single point of contact for all internal and external stakeholders on legal and ethical issues.
tp21 GmbH, Berlin, Germany
tp21 is specialized in the planning and management of European interdisciplinary RTD projects mainly in the medical and medical technology field. The TP21 management methodology considers all aspects of the scientific technological value creation chain necessary to enable the implementation of research projects, communication/marketing, and exploitation. TP21 also supports the take-up of research results and new technologies, supervising feasibility studies, technology transfer, coaching innovation finance and start-up initiatives.
tp21 is experienced in science communication, business preparation and PR work via websites, booths, exhibitions, catalogues, promotion videos, start-up coaching, technology transfer events, VC due diligences, and business plan coaching.
Alzheimer Europe, Luxembourg, Luxembourg
Alzheimer Europe is a lobbying organisation promoting dementia awareness, care and research within the EU institutions. The organisation considers its mission “changing perceptions, practice and policy in order to improve the quality of life of people with dementia and their carers”. Alzheimer Europe has been granted consultative status with the Council of Europe and accredited by the European Medicines Agency as a patient organisation complying with the agency’s strict criteria on transparency, democracy, accountability and representativeness.