Coordination

Petra Ritter, Ph.D, MD

Charité Universitätsmedizin - Germany

The CHARITE is Europe´s largest University Hospital that combines leadership experience a strong track record for development of innovative technologies and combining science with outreach projects to engage public.

Petra Ritter serves as the director of the Section for Brain Simulation. This group has been at the forefront of network-based brain simulation, computational neuroscience and its clinical application for more than 10 years. In collaboration with other international research centers, the team led by Professor Ritter has developed a way to simulate a brain of an individual person or patient with reduced complexity but feasible, sufficiently accurate, scalable and already used in practical clinical applications. Professor Ritter’s group employs state-of-the art software engineering methods for developing tools for data processing, analysis and visualization.

visit website

Indoc Research

Assistance to Coordinator: Technical coordination; Subcontracted by Charité

visit website

Kenneth Evans, Ph.D

Consortium members

Viktor Jirsa, Ph.D

Aix-Marseilles University Aix en Provence & Marseilles, France

The Institut de Neurosciences des Systèmes is a multidisciplinary research institute located in Marseille. The core faculty is composed of members of academic and clinical institutions. The research has been developed around a common concept, the dynamic brain, integrating experimental, theoretical and clinical approaches towards the understanding of brain function and dysfunction.

The Theoretical Neuroscience group led by Viktor Jirsa aims to uncover the mechanisms underlying the spatiotemporal organization of large-scale brain networks in physiology including aging and disease with a particular interest in epilepsy and neurodegenerative diseases.

visit website

Forschungszentrum Jülich - Germany

The Forschungszentrum Jülich (FZJ), is a member of the Helmholtz Association of German Research Centres and is one of the largest interdisciplinary research centers in Europe. FZJ has an outstanding track-record in multi-modal high-throughput neuroimaging analysis, the investigation of brain structure-function relationships in health and disease as well as the development and application of big data approaches towards the understanding of brain organization.

The Institute of Neuroscience and Medicine (INM-7) lead by Simon Eickhoff works towards a more detailed characterization of the organization of the human brain and its interindividual variability in order to better understand its changes in advanced age as well as neurological and psychiatric disorders. Machine learning algorithms are developed and applied for predictive modeling of interindividual variability and pathology.

The Jülich Supercomputing Centre (JSC) operates supercomputers which are among the largest in Europe. The JSC undertakes research and development in HPC architectures, performance analysis, HPC applications, data analytics, federated infrastructures, and networking. The JSC's SimLab Neuroscience supports neuroscientists in using supercomputing and data resources for their research, and is engaged in collaborative research and development of HPC-based methods and tools for neuroscience.

visit website

Simon Eickhoff, Ph.D.
Thomas Llippert, Ph.D.
Stanley Durleman, Ph.D

Institut de Cerveau et de la Moelle Epinière - France

The Institut du Cerveau et de la Moelle épiniere (ICM) is an international brain and spinal cord research center whose innovative concept and structure make it the only institute of its kind in the world. The institute brings patients, doctors and researchers together with the aim to rapidly develop treatments for disorders of the nervous system and enable patients to benefit from them as quickly as possible. Its teams carry out cutting-edge research on cellular and experimental models, neuroimaging & behavioral neuroscience, as well as data analysis. Being involved in several cohorts of patients allows the ICM to perform proeficient translational research.

The ARAMIS Lab is one of the leading teams in Europe for the modelling of neurodegenerative diseases. It has proposed original approaches for building brain models by the integration of multimodal data sets combining information from clinical, imaging and genomic data. The team has a strong expertise in imaging science, network theory, statistical and machine learning, and mathematical modelling. It has developed new computational approaches for modelling brain structure and function and has applied them in a large array of clinical studies, and in particular in the field of neurodegenerative diseases (Alzheimer’s Disease, Parkinson’s Disease, Multiple Sclerosis).

visit website

Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany

The Department of Bioinformatics Fraunhofer SCAI is a leading institute in applied research and development in the field of information extraction / semantic text analysis, integrative data semantics, and modeling of neurodegenerative diseases and neuropsychiatric conditions. The Department of Bioinformatics is working closely with industrial partners to enhance their competitiveness through mediating knowledge and technology transfer from academic research to industrial applications. Positioned at the boundary between commercial and academic research, Fraunhofer SCAI maintains strong links with both communities.

visit website

Martin Hofmann-Apitius, Ph.D.
André Gemünd
Jean Georges

Alzheimer Europe - Luxembourg

Alzheimer Europe is a lobbying organisation promoting dementia awareness, care and research within the EU institutions. The organisation considers its mission “changing perceptions, practice and policy in order to improve the quality of life of people with dementia and their carers”.

Alzheimer Europe has been granted consultative status with the Council of Europe and accredited by the European Medicines Agency as a patient organisation complying with the agency’s strict criteria on transparency, democracy, accountability and representativeness.

visit website

tp21 GmbH - Germany

tp21 is specialized in the planning and management of European interdisciplinary RTD projects mainly in the medical and medical technology field. The TP21 management methodology considers all aspects of the scientific technological value creation chain necessary to enable the implementation of research projects, communication/marketing, and exploitation. TP21 also supports the take-up of research results and new technologies, supervising feasibility studies, technology transfer, coaching innovation finance and start-up initiatives.

tp21 is experienced in science communication, business preparation and PR work via websites, booths, exhibitions, catalogues, promotion videos, start-up coaching, technology transfer events, VC due diligences, and business plan coaching.

visit website

Petra Zalud, Ph.D.
Lia Domide, Ing.

Codemart SRL - Romania

Codemart is certified under ISO 9001, for the procedure of delivering client tailored software solutions. Codemart is intimately familiar with architecting, building and maintaining fairly large codebases for various industries in many countries. Ranging from neuroscience projects, to printers coordination solutions, Codemart maintained recurrent collaborations with its final clients over the years. Codemart is a closely knit team of specialists, having long experience in computer science and training at the Technical University of Cluj Napoca.

Codemart have made it part of the procedure to write automated test, have continuous integration builds and try various optimization techniques for each of the solutions tailored.

visit website

University of Oxford - United Kingdom

The University of Oxford is an internationally recognised centre of excellence for biomedical and clinical research and teaching.

The largest group of the Translational Neuroscience and Dementia Research laboratory is the Translational Informatics team, led by Dr Alejo Nevado-Holgado. The laboratory has research experience developing AD biomarkers and has led the field on using blood as the substrate tissue for such biomarkers. Such blood-based biomarkers are the only practical solution towards screening wide sections of the general population, and early detecting those who are developing AD years earlier than currently possible.

visit website

Alejo Nevado-Holgado, Ph.D
Jochen Mersmann

Codebox Computerdienste GmbH, Stuttgart, Germany

Codebox has a wide range of expertise in the development of software and has been in charge of the technical architecture, data-infrastructure and visualization technology of The Virtual Brain project including its conception, development and implementation. The modus operandi of Codebox is “distributed software development” to leverage optimal expertise for a particular project. Codebox has a good reputation for delivering robust software-architecture in scientific programming.

Codebox and CodeMart have a collaborative history of software development that has led to the successful professional design and release of The Virtual Brain (TVB) platform for large-scale mean-field simulations based on connectomic data and analysis of empirical and simulated activity.

visit website

Fundació Institut de Bioenginyeria de Catalunya, Barcelona, Spain

IBEC is one of the Spanish research centres of excellence at the highest international level in terms of research, training, human resources, outreach and technology transfer.

The “Synthetic Perceptive, Emotive and Cognitive Systems (SPECS)” group led by Prof. Paul Verschure is a multidisciplinary research group focusing its research activities to study and synthesize the neuronal, psychological and behavioural principles underlying perception, emotion and cognition. SPECS perform interdisciplinary research in the domains of technology, cognitive science and humanities, and have a long-standing tradition in the domains of computational neuroscience, cognitive science and interactive systems.

visit website

Paul Verschure, Ph.D
Satu Palva, Ph.D

University of Helsinki, Finland

The Neuroscience Center (NC) is an independent research and teaching institute at the University of Helsinki.

The Palva-Lab has made pioneering contributions in the fields of electrophysiological human brain connectomics and characterization of complex spatio-temporal brain dynamics. The Palva team has an extensive track record for using source-reconstructed MEG/EEG analyses of connectivity and dynamics to uncover the mechanistic roles in cognitive functions. The group has studied the roles of dysconnectivity and dysdynamics in brain disorders such as schizophrenia, epilepsy, depression, and anxiety.

visit website

University of Genoa, Italy

The University of Genoa (UNIGE) is one of the most ancient of the European large universities.

The Gabriele Arnulfo team are experts in signal processing mainly involving neuronal time series. Unit members have extensive expertise in Biomedical engineering topics including advanced signal processing of electrophysiology as well as imaging modalities. Several members have active involvement in the construction of informatic applications based on web for the support of multicentric with particular attention to studies dealing with the application of standardized systems in medicine and biology.

visit website

Gabriele Arnulfo, Ph.D
Bertrand Thirion, Ph.D

Institut National de Recherche en Informatique et Automatique - France

Inria is the only French public research body fully dedicated to computational sciences. Inria’s mission is to pursue excellent research in computer science and applied mathematics in order to play a major role in resolving scientific, societal and industrial challenges.

Bertrand Thirions group has a recognised expertise both in machine learning and functional brain imaging data analysis. The Parietal team is a leading group in the design of dedicated machine learning techniques for data-driven regions segmentation of rest fMRI, and the creations of the tangent approach for functional connectivity analysis, that outperforms all other connectivity estimators on the challenging task of connectome estimation.

visit website

Eodyne Systems SL, Barcelona, Spain

Eodyne is specialised in the development and commercialization of advanced science-based neurorehabilitation software with an emphasis on functional recovery post stroke which will provide a driver for integration across the broad set of activities. Eodyne advances a network science-based paradigm for neurorehabilitation by taking a multiscale network-based perspective from genetics and connectomics to behaviour.

Eodyne’s expertise is on the development of algorithms and applications with virtual and augmented reality, immersive systems and infrastructures, scientific visualization, modeling and simulation, big data approaches on clinical data.

visit website

Santiago Brandi
Nikolaus Forgo, Ph.D

University of Vienna, Austria

The Department of Innovation and Digitalisation in Law, being part of University's of Vienna School of Law, was founded in October 2017 to face new legal questions and challenges in the 21st century. The department deals with legal questions surrounding IT/IP law from a European perspective, with an emphasis on data protection and data security law. The head of the department is Prof. Dr. Nikolaus Forgó, a full professor of Intellectual Property and technology law, whose objectives, among others, are to stratify, bundle and foster the existing research initiatives on digitalisation and IT at the law school. One important focus is the participation in third-party funded legal research, especially EU-founded projects.

The Department of Innovation and Digitalisation in Law will serve as single point of contact for all internal and external stakeholders on legal and ethical issues.

visit website

Universidad Complutense de Madrid, Spain

The Universidad Complutense de Madrid (UCM) is one of the largest Universities in Spain with high-level technological scientific infrastructure.

The Laboratory of Cognitive and Computational Neuroscience (LCCN) is part of the Center for Biomedical Technology (CTB), a multi-university research centre with deep experience on functional neuroimaging techniques, behavioural methods and data analysis, carry out research on cognitive and computational neuroscience, neuroimaging, nanomedicine, computational system biology, connexiopathies, biomagnetism, biomechanics, biomedical informatics, and tele-rehabilitation technologies. In particular, LCCN is pointed to the study of different stages of dementia as well as to reconfiguration phenomena associated with brain damage.

visit website

Fernando Maestu, Ph.D

Technical Advisory Board

Stefano Cappa, MD

Stefano Cappa, MD

Professor of Cognitive Neuroscience at the University Vita-Salute S. Raffaele of Milan

Magali Haas, MD, Ph.D

CEO & President Cohen Veterans Bioscience

Magali Haas, MD, Ph.D
Peter-Andreas Löschmann, Ph.D

Peter-Andreas Löschmann, Ph.D

Senior Director Corporate Affairs & Senior Medical Director - Pfizer Pharma GmbH Germany

Paul Matthews, OBE, MD, DPhil, FRCP, FMedSci

Head of the Department of Brain Sciences in the Faculty of Medicine of Imperial College London and Chair of the Imaging Working Group for UK Biobank

Paul Matthews, OBE, MD, DPhil, FRCP, FMedSci
Randy McIntosh, Ph.D

Randy McIntosh, Ph.D

Senior Scientist at Baycrest Health Sciences and co-laed of TheVirtualBrain

Per Öster, Ph.D

Director of the Research Infrastructures unit at CSC and Project Director of the EOSC-Hub project

Per Öster, Ph.D
Thomas Schulthess, Ph.D

Thomas Schulthess, Ph.D

Director of the Swiss National Supercomputing Centre (CSCS) at Manno and full Professor of computational physics at ETH Zurich

Fabrizio Tagliavini, MD

Scientific Director IRCCS Foundation, "Carlo Besta" Neurological Institute, Milan, Italy

Fabrizio Tagliavini, MD

Ethical Advisory Board

Dipak Kalra, PhD, FRCGP, FBCS

Dipak Kalra, PhD, FRCGP, FBCS

Dipak Kalra is President of The European Institute for Innovation through Health Data

Waltraut Kotschy, Ph.D

Head of DPCC e.U., Data Protection Consulting, former head of Austrian Data Protection Authority

Waltraut Kotschy, Ph.D
Prof. Cecilia Magnusson Sjöberg

Prof. Cecilia Magnusson Sjöberg

Professor (LL.D) of Law and Information Technology at Stockholm University

Robin Pierce, JD, Ph.D

Tilburg Institute of Law, Technology, and Society (TILT), Tilburg Law School, Tilburg University

Robin Pierce, JD, Ph.D